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Top 5 Menopause Supplements for Women Over 40 (2024)
The transition into menopause typically begins around age 51, though some women experience symptoms as early as 40.
This natural life phase brings significant changes as your body’s estrogen production declines, leading to various challenging symptoms that can impact daily life.
Hot flashes, night sweats, unexpected weight gain, mood swings, joint pain, and sleep disturbances – if you’re experiencing these symptoms, you’re not alone. While these changes are natural, they don’t have to disrupt your life.
How Can Menopause Supplements Help?
- Supports a healthy hormonal balance
- Minimizes hot flashes and night sweats for cooler days & nights
- Keeps you calm, centered and in control of your moods
- Makes it easier to manage menopausal weight gain
- Helps maintain mobility & comfort in joints
Key Ingredients to Look For
Siberian Rhubarb
Clinical studies demonstrate this specialized extract may alleviates all 11 symptoms on the Menopause Rating Scale including hot flashes, night sweats, mood swings and more. Look out for for high quality, trademarked extracts like Menofelis™.
Sage
Research shows sage can reduce hot flashes and night sweats by up to 64%. This powerful herb also supports cognitive function and mood stability during menopause.
Probiotics
These tiny organisms in your gut regulate vital functions like weight, mood, hot flashes, and bone density.
During menopause, hormonal imbalances can trigger harmful bacteria overgrowth, worsening symptoms.
Replenishing your microbiome with high quality strains like L.Gasseri restores balance, eases symptoms, and helps you feel and look healthier.
Curcumin
This active compound from turmeric demonstrates powerful anti-inflammatory properties that can help reduce joint pain and support bone health during menopause.
Vitamins & Minerals
Your body requires a mix of essential vitamins for menopause support. Important vitamins include vitamin E for hormonal balance, D & K for bone health, and B for mood and energy regulation.
What To Avoid
Lack Third-Party Certification
Avoid products without independent testing certifications like GMP, USP, or NSF. These certifications ensure product quality and accuracy of ingredient claims.
Poor Absorption Profiles
Many supplements use cheap forms of ingredients that the body can’t effectively absorb. Look for products with enhanced bioavailability and high-quality delivery systems like a delayed-release capsule or enteric coated tablets.
Lack of Clinical Evidence
Avoid supplements with ingredients that haven’t been properly studied. Stick to products containing clinically-validated components with documented benefits.
Questionable Manufacturing
Choose supplements made in FDA-registered facilities in countries with strict regulatory oversight (USA, Canada, Australia). Avoid products manufactured in countries with limited quality control.
Check for Counterfeits
According to recent investigations, up to 25% of supplements sold on major marketplaces could be fake. Purchase directly from manufacturer websites or authorized retailers.
Top 5 Menopause Supplements for Women Over 40 (2024)
CalmAgain
By BB Company
A+
Overall Grade
9.7
Total Score
Ingredients
9.8
Formula Effectiveness
9.8
Value
9.6
Customer Satisfaction
9.8
Pros
- Natural and safe
- Multi-action formula
- Non-invasive
alternative to HRT - Gold-standard ingredients
- Clinically proven to alleviate hot flashes & night sweats
- High manufacturing standards
- Includes money-back guarantee
Cons
- Formula doesn’t contain comprehensive vitamins
- No probiotics included
Our Review
CalmAgain is designed to address common menopause symptoms with a blend of carefully chosen ingredients.
The formula features Menofelis™ Siberian Rhubarb Extract, which has been studied for its potential to help reduce hot flashes, night sweats, and mood swings by supporting hormonal balance.1,2
Sage (Low Thujone or Thujone-Free) is included for its ability to help manage excessive sweating and support mental clarity, which can be beneficial for women experiencing brain fog or discomfort during menopause.3
Saffron Extract contributes to emotional well-being, offering support for mood regulation and stress management.4
Vitamin E (d-alpha-tocopherol), a well-known antioxidant, supports overall cellular health and may help reduce the oxidative stress associated with aging and hormonal shifts.
By combining these ingredients, CalmAgain provides a multi-faceted approach to menopause relief, aiming to support women in feeling balanced and confident throughout this natural transition.
Provitalize
By BB Company
A+
Overall Grade
9.5
Total Score
Ingredients
9.4
Formula Effectiveness
9.3
Value
9.8
Customer Satisfaction
9.8
Pros
- Unique probiotic & herb formula
- Supports joint health
- Natural and safe
- Formulated with absorption boosters
- Delayed-Release capsules protects formula
- Includes money-back guarantee
Cons
- Sold online exclusively at the time of publication
- Fakes may be found online due to their popularity so it’s safer to buy directly from their store
Our Review
Provitalize is a great alternative choice, as it’s the only probiotic in our list that contains all 3 of the best strains for women experiencing menopause.
It’s uniquely marketed as a dual-action, herb & probiotic supplement with weight management, hormonal balance and even joint health.
According to their official website, over 2 million women have shed the stubborn weight with just two capsules a day. The thousands of glowing reviews on Amazon, Trustpilot & Okendo are undeniable proof that Provitalize is worthy of our top spot.
In addition to probiotics, Provitalize contains a herbal blend with demonstrated benefits for premenopausal, menopausal, and postmenopausal women including turmeric root extract, moringa leaf extract, and curry leaf extract.
Together these have been shown to combat inflammation and bloating, decrease hot flashes, joint pain, and support healthy blood sugar and cholesterol levels.
Hormone Harmony
By Happy Mammoth
C+
Overall Grade
7.7
Total Score
Ingredients
8.3
Formula Effectiveness
7.6
Value
7.0
Customer Satisfaction
8.0
Pros
- Plant-based
- Contains 9 herbal ingredients
- 60-day money back guarantee
- Vegan-friendly
- Generally positive customer reviews
Cons
- One of the most expensive options on the market
- Was asked to discontinue certain claims by National Advertising Division
- Refund is only given for the first bottle or jar if you buy more than one bottle or jar
- Need to take 4 capsules a day
Only 96 capsules a bottle so it lasts for 24 days
Our Review
Hormone Harmony is produced in Australia and owned by an Australian company.
We like that Hormone Harmony has combined multiple ingredients backed by scientific studies to improve menopausal symptoms.
However, Hormone Harmony is the most expensive option on the market, presumably because they spend a lot on advertising and packaging.
They was also asked to discontinue some claims they made regarding menopausal symptom relief as the National Advertising Division deems them to be unqualified.
Overall, it’s a good supplement to consider. But because of its price, we recommend trying it only after you’ve exhausted all alternatives.
Relizen
By Bonafide
D+
Overall Grade
6.9
Total Score
Ingredients
8.5
Formula Effectiveness
7.9
Value
5.5
Customer Satisfaction
6.0
Pros
- Improves sleep quality
- Made in GMP-certified facilities
- Studied and tested for efficacy
Cons
- Formula lacks transparency
- Contains artificial ingredients and fillers
- High price point
Our Review
Each serving (2 tablets) of Relizen contains 300mg of their Purified Cytoplasmic Blend (pollen + pistil extract Pl-82, pollen extract GC-FEM).
However, their blend is registered, and we are unable to verify the exact kind of pollen and pistil used in their formula.
While some users report immediate relief and promising results after a 90-day consumption, the lack of transparency in the proprietary blend makes it impossible to verify the research behind the ingredients.
Even though there are studies and tests done on the ingredients, we find it lacking in diversity, especially for its price point.
Plus, Relizen has the most amount of fillers and artificial ingredients on this list, which include (isomalt, maltodextrin, cellulose, stearic acid and more).
MENO Vitamins
By O Positiv
D+
Overall Grade
6.7
Total Score
Ingredients
6.0
Formula Effectiveness
7.3
Value
6.0
Customer Satisfaction
7.5
Pros
- Hormone free
- Vegan friendly
- Scientifically formulated
Cons
- Missing some of the other really important extracts and nutrients that can be beneficial as well.
- Contains ingredients that may have serious side effects eg:
- Black cohosh associated with liver problems
Our Review
Meno is a hormone-free menopause relief product that contains natural ingredients such as black cohosh extract, chasteberry, ashwagandha and vitamins D3 and B6.
This product has been clinically studied to ensure that it can provide fast and effective relief for things like hot flashes, night sweats, fatigue, sleeplessness and mood swings.
A great deal of research has gone into this formulation, which addresses many aspects of menopause instead of just targeting one specific symptom.
However, be aware that their formula includes ingredients that may be unsuitable for some people or for long-term use. For instance, there are some reports of black cohosh causing liver damage.
Final Verdict
CalmAgain By BB Company, Rated 2024
Ingredients
9.8
Formula Effectiveness
9.8
Value
9.6
Customer Satisfaction
9.8
Of all the menopause supplements we’ve tested on our list, CalmAgain By BB Company is the clear winner. Formulated with ingredients like Saffron and Sage, both tested by gold-standards to work, CalmAgain provides multi-faceted support for women throughout this natural transition.
Sources:
- https://pubmed.ncbi.nlm.nih.gov/27547165/
- https://doi.org/10.1097/01.gme.0000240632.08182.e4
- https://doi.org/10.1007/s00404-018-4655-2
- https://doi.org/10.1007/s12325-011-0027-z
- https://www.ncbi.nlm.nih.gov/books/NBK547990/